Get Newsletter
AlzRisk Paper Detail

Reference: Ogunniyi, 2006
Cohort: Indianapolis-Ibadan Dementia Project - Indianapolis Cohort
Risk Factor: Alcohol

Average Follow-up Time Detail
Follow-up time was not presented in the article; was presented in the cited article describing the cohorts (Hendrie, et al., JAMA, 2001).

Ethnicity Detail
Participants were African-Americans from Indianapolis.

Age Detail
This is the mean age of 1,255 study participants who completed the screening; 498 of the them were clinically assessed and included in this analysis, but the baseline age for this subset was not reported.

Screening and Diagnosis Detail
Screening Method:
CSIDCommunity Screening Interview for Dementia

AD Diagnosis:
NINCDS ADRDA National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)

"Essentially, a two-stage designwas utilized comprising the administration of the Community-Screening Instrument for Dementia (CSI’D) to eligible participants. The incidence study was conducted in two waves – two and five years after the prevalence study. Sub-samples of the study participants were selected for clinical assessment according to established cut-off scores that were derived from discriminant function analysis. Details of these had been described (Hall et al., 1996). The clinical assessment included a structured interview with an informant, neuropsychological testing, and examination by a physician as well as laboratory and imaging studies. All the information obtained was utilized in the consensus diagnosis process within each site, and inter-site agreement was essential before the final diagnoses were recorded. The Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition (DSM-IIIR) and International Classification of Diseases, 10th Revision (ICD-10) criteria were used to diagnose dementia (American Psychiatric Association, 1987; World Health Organization, 1992). For AD, the National Institute for Neurological and Communicative Diseases and Stroke – Alzheimer’s Disease and Related Disorders Association (NINCDS-ADRDA) criteria were used (McKhann et al., 1984)."

Covariates & Analysis Detail
Analysis Type:
Logistic regression

AD Covariates: