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AlzRisk Cohort Detail
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Cohort: Cohort of women in Gothenburg
Risk Factors:

Introduction to the Cohort
The Gothenburg women's study is a prospective population study based at the University of Gothenburg, Sweden. The study was initiated in 1968 to investigate health factors related to menopause and anemia in middle-aged women, but was later expanded to study risk factors for developing health conditions later in life, such as cardiovascular disease, cancer, diabetes and dementia.

In 1968, investigators systematically recruited female residents of Gothenburg, Sweden born in 1908, 1914, 1918, 1922 and 1930 by sampling from the census register based on specific birth dates, to obtain representative samples of 38-, 46-, 50-, 54-, and 60-year-old females. Out of 1600 female residents who were identified, 1492 participated in the study. Investigators recorded participants' anthropomorphic measurements, blood pressure, medical history and dietary information during an examination performed at baseline. Most participants provided blood samples. The cohort was followed-up in 1974-75, 1980-81, 1992-93, 2000-2003 and 2009-2010.

Ethnicity Breakdown
The participants were presumably mostly Caucasian, as they were born in Sweden in the early 1900s. No additional information about ethnicity was given.

Diagnosis & Evaluation Methods
For details on diagnosis and screening methods see Zylberstein et al. 2011.

References
Zylberstein D,Lissner L, Björkelund C, et al. Midlife homocysteine and late-life dementia in women. A prospective population study. Neurobiology of aging; 2011; 32: 380-386.

Bengtsson, C, Blohme G, Hällström,T.,et al. The study of women in Gothenburg 1968–1969 a population study. General design, purpose and sampling results. Acta Med. Scand. 1973; 193(4: 311–318.